Transcription is a process in eukaryotic cells is coupled to mRNA processing and transport. In recent years, we know that the transcription of at least a number of genes occurs at the nuclear periphery near the nuclear pore. In yeast ASaccharomyces...
Research in the past eight years has driven the classical idea that nuclear processes occurring from transcriptional activation to the mature mRNA out of the nucleus were independent events. The work of many groups has contributed significantly to turning...
Transcription Initiation Apparatus We discovered that the RNA polymerase II transcription initiation apparatus contains a multiprotein complex, called the Srb/mediator complex, which is involved in mediating the response to...
Several themes are featured. Transcriptional activators bind to specific DNA sequences, and the chromatin context of the DNA biding site can have a positive or negative influence on binding of the activator or the proteins it recruits to the promoter....
Three papers were signed at a joint CSIC and the University of Salamanca describe the identification and characterization of a new family of serine-threonine kinases of human carcinoma, in the course of evolution, separated from the branch that...
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