In this work, directed by Dr. Angela Nieto of the Instituto de Neurociencias de Alicante, it becomes evident that the first Snail1 transcriptional repressor of Runx2, which controls the activity of this protein complex during differentiation of...
In this work, directed by Dr. Angela Nieto of the Instituto de Neurociencias de Alicante, it becomes evident that the first Snail1 transcriptional repressor of Runx2, which controls the activity of this protein complex during differentiation of...
The fate of a cell is determined by signals from their environment and their ability to respond to them. Some signaling pathways are involved in vital decisions during the development of organisms, this being an example of epithelial-mesenchymal...
Snail is a transcription factor that controls epithelial-mesenchymal transitions, processes also involved in the metastasis of epithelial tumors. This control is exercised by repressing expression of E-cadherin, and other epithelial genes. The work done...
Angela Nieto's team has been working for 14 years in the functional analysis of the Snail gene family. After spending several years at the National Institute for Medical Research, London, Nieto is now a research professor at the Institute of Neurosciences...
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