Since the middle of last century was known that in vertebrates, meiosis and early embryonic divisions required polyadenylation and translational activation of maternal mRNA stored in the oocyte. However, it was not until the nineties when it began to...
Following his doctoral dissertation at the Universidad Autonoma de Madrid, Raul Mendez spent the next eight years of research activity in American laboratories of Robert E. Rhoads (Louisiana State University Medical Center) and Joel D. Richter (University...
Many studies in the yeast Saccharomyces transcriptomic in analyzing the gene expression program in a variety of conditions. Most if not all the cited studies analyzed only the different levels of mRNA by conventional genomic techniques. Indeed, in many...
Transcription is a process in eukaryotic cells is coupled to mRNA processing and transport. In recent years, we know that the transcription of at least a number of genes occurs at the nuclear periphery near the nuclear pore. In yeast ASaccharomyces...
Research in the past eight years has driven the classical idea that nuclear processes occurring from transcriptional activation to the mature mRNA out of the nucleus were independent events. The work of many groups has contributed significantly to turning...
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