Alzheimer's disease (AD) and other neurodegenerative processes are characterized by a deregulation of intracellular levels of neuronal Ca 2 +. This alteration seems to carry an implicit cause-effect relationship to toxicity by the β-amyloid peptide and...
The group of Roberto Solano, Department of Plant Molecular Genetics at the National Center for Biotechnology, made the study of signaling pathway of the phytohormone jasmonate (JA) in Arabidopsis thaliana and the molecular mechanisms underlying the...
The specificity of molecular techniques is dependent on the stringency ("stiffness") of the hybridization conditions, which is determined by a combination of different factors including temperature and salt concentration. The presence of a target sequence...
The hemidesmosomes are multifunctional multiprotein complex of great importance to the integrity of epithelia. Exercise of mediators of cell adhesion and confer resistance to mechanical stress, linking the extracellular matrix with cytokeratin filaments...
Many disease states require panels of different tests to be conducted simultaneously (multiplexing) to achieve a clinically complete picture. To date, efforts to multiplex tests have been constrained by issues of background noise or interference, or the...
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