A cyclin-dependent kinases Cdk4 and Cdk6 are attributed a crucial role in the initiation of cell cycle in response to mitogenic stimuli. They are, therefore, be targets toward which the biomedical sciences and pharmaceutical industry directed its efforts...
Cytotoxic T lymphocytes (CTLs) eliminate virus-infected tumor cells or alloantigen through a lyric mechanism, which involves the secretion of a cytoplasmic granules containing cytotoxic proteins, perforin and granzymes, of which the two most important are...
A team of researchers from the Autonomous University of Barcelona published a study showing that transposons can silence genes adjacent to or significantly reduce its expression by induction of synthesis of an antisense RNA. This new mechanism is now...
BMPs (bone morphogenetic proteins) are determining factors in the mechanisms of embryonic development and differentiation of tissues such as bone, muscle and nervous. It knows its restrictive action on neuronal differentiation, promoting the maintenance...
To maintain genomic stability, mammalian cells require the action of five proteins encoded by paralogous genes to that of RAD51, a molecule involved in DNA repair, implying orquesrado operation of certain protective mechanisms. In previous work on...
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