The Ras superfamily of GTPases regulate important cellular processes like cell proliferation, differentiation and cell survival, mutations involving the development of cancer. In cancer, apart from the Ras proteins (H-Ras, N-Ras and K-Ras) are also...
Embryonic development and morphogenesis of individual organs are common schemes based processes. In them, groups of undifferentiated cells, they initiate a series of complex interactions with internal and external signals, in order to establish patterns...
Researchers Differentiation and Cancer Programme of the Centre for Genomic Regulation in Barcelona (CRG) have shown, in an article that took the cover of a recent issue of Cancer Cell, the connections between DNA methylation mechanisms and the complex...
AKR1B10 is a aldocetoreductasa (AKR) especially interesting for two reasons: it is overexpressed in lung cancer and precancerous lesions of smokers and becomes very efficient, the retinal to retinol, retinal reductase being the most active among AKR....
Understanding how cells organize and coordinate to form the tissues and organs in living organisms (morphogenesis) is a basic question in developmental biology. The morphogenesis requires a number of cellular processes that occur in a coordinated way in...
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