The astrocytic Ca2 + signal is essential in the exchange of infor mation between astrocytes and neurons. Cannabinoid receptors are key to brain physiology, but its expression and function in astrocytes in situ is unknown. Marta Navarrete and Alfonso...
Research in the past eight years has driven the classical idea that nuclear processes occurring from transcriptional activation to the mature mRNA out of the nucleus were independent events. The work of many groups has contributed significantly to turning...
The export of messenger RNA from nucleus to cytoplasm is an essential process in eukaryotic cells. Sus1 protein plays a significant role in the coupling between the initiation of transcription and mRNA export. Sus1 is a small protein (11kDa of only),...
The Prince Felipe Research Center in Valencia counts among its researchers with a young and active team led by Susana Rodriguez-Navarro, dedicated to understanding how messenger RNAs are produced and exported from the nucleus to the cytoplasm, a process...
In this work, directed by Dr. Angela Nieto of the Instituto de Neurociencias de Alicante, it becomes evident that the first Snail1 transcriptional repressor of Runx2, which controls the activity of this protein complex during differentiation of...
Sirtuins (SIRT), protein family of histone deacetylases (HDAC) are involved in processes such as longevity, cancer, gene regulation, energy homeostasis and apoptosis.Inhibitors of sirtuins have antitumor properties, but so far no known inhibitor, such...