The astrocytic Ca2 + signal is essential in the exchange of infor mation between astrocytes and neurons. Cannabinoid receptors are key to brain physiology, but its expression and function in astrocytes in situ is unknown. Marta Navarrete and Alfonso...
The control of gene expression depends on the access of chromatin gene regulatory areas to the transcriptional machinery. The covalent modifications of histones as acetulaciones and methylation are key factors to regulate that access. Reading the...
In the laboratory of Fernando Rodriguez Pascual, Researcher, Center for Biological Research of the CSIC, are very interested in studying mechanisms regulating gene expression vasoconstrictor peptide endothelin-1 (ET-1) at both transcriptional and...
Alzheimer's disease (AD) and other neurodegenerative processes are characterized by a deregulation of intracellular levels of neuronal Ca 2 +. This alteration seems to carry an implicit cause-effect relationship to toxicity by the β-amyloid peptide and...
One of the tenets associated with cancer advocates that the inactivation of oncogenes leads to remission of the tumors, implying that oncogenes would be the real Achilles heel of cancer. This model has kept the oncogenes as a therapeutic target clear and...
Plasma membrane repair in plantsThe damage and subsequent repair of the plasma membrane are normal processes in the life of most animal cells such as muscle cells of mammals which are subject to continuous damage as a result of physical activity that are...