There are items that make a difference, appearing one at the right time, involving a breakthrough or provide any major surprises. It must then stop to reflect, to contextualize and deepen. With this in mind we opened section. As we have been doing regularly, we discuss the reference and appreciate your interest, but delve into the subject by giving it a context and a time that, in this case, it is particularly recent.

The second half of 2005 and 2006 little that we have been a time of rapid and definitive findings about the involvement of epigenetics in cancer. It is in this rich breeding ground that there are two important works in Spanish or Spanish contribution. Both are published by Nature in less than a month: the work of Ferres et al. In this new section highlight, and the col.1 Vireo and has participated in group Manuel Esteller of the CNIO. The latter group had already published in 2005 in Nature Genetics, the relationship between cancer and one of the epigenetic mechanisms, 2 the modification of histones. Also, Esteller was awarded the 2005 Award for his work Carcinogenesis. Although both works are important drivers of the progress being made in this field, highlight the Ferre et al., Not so much for having appeared in print three weeks before, but because it is one of the rare cases in which Nature published a full working Spanish.