RCAT™ is the ideal amplification method for biochips. No other practical amplification method can recognize, amplify and detect target molecules directly on a solid surface. Currently, gene arrays place spots or "elements" in a high-density matrix on...
Gene-Based Diagnostics Through RCAT™—Fast and Accurate Gene-based diagnostic tests are the fastest growing segment of the in vitro diagnostic market. They use the tools of molecular biology to identify nucleotide substitutions, deletions, or...
Proteins and small molecules are commonly measured indirectly in diagnostics, through the use of antibodies ("immunodiagnostics"). Immunodiagnostic testing is the current "gold standard" for many diagnostic determinations. The application of RCAT™ in...
Allele Frequency Distortion (AFD), developed at the Yale University School of Medicine and licensed to MSI, is a method for identifying regions of DNA that differ between individuals who have a particular disease and those who do not. AFD uses DNA...
RCAT™ driven by DNA polymerase can replicate circular oligonucleotide probes with either linear or geometric kinetics under isothermal conditions. In the presence of two suitably designed primers, a geometric amplification occurs via DNA strand...
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