Knowledge of the three-dimensional structure of a biological molecule can yield a wealth of information about its mode of action and direct the systematic design of pharmaceutical agents. Consequently structural studies have had a major impact in many...
The core research in the NCRR center for Computational Biology Solutions is in protein folding, protein dynamics and bioinformatics. It provides a resource for a wide range of biological applications running on desktop to the highest-end computers. The...
After specific proteins are identified for further research, they are excised from the gel and treated with a succession of enzymes that cut amino acid chains into short polypeptides about 5-10 amino acids in length. The polypeptide fragments for each...
Annotation : A functional description of a clone, which may include identifying attributes such as locus name, keywords, and Medline references. BAC : Bacterial Artificial Chromosome; see cloning vector. BLASTÂ : The Basic Local Alignment Search Tool...
Chromosome 7 accounts for approximately 5% of the human genome. It is estimated to be 136 centiMorgans (cM) in length and contains 170 million basepairs (170 Mb) of DNA. We are mapping and sequencing two targets along chromosome-7, one at 7q31.3, and the...
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