The p53 tumor suppressor gene regulates the expression of p53-induced genes (PIG: p53 induced genes) that initiate apoptosis. The PIG3 or TP53I3 is the only member of the superfamily of dehydrogenases / reductases medium chain induced p53 proapoptotic be...
Adenocarcinomas of the lung or breast cancer, brain metastasis sources represent two very different courses of disease. In the case of breast, brain tumor occurs many years after removal from the primary tumor, suggesting that cancer cells lack certain...
El pasado 10 de noviembre se presentó en la sede central del CSIC en Madrid el nuevo portal de internet de la Sociedad Española de Bioquímica y Biología Molecular. El acto, que se enmarcaba dentro de las actividades programadas con motivo de la Semana...
Advances in recent decades have revealed the genetic scenario of the formation of melanoma including mutations and signaling pathways. Researchers at the Melanoma Group, headed by Dr. Soengas in the National Cancer Research Center (CNIO), have made human...
Diseases of Charcot-Marie-Tooth (CMT) are a heterogeneous group of inherited neuropathies. The molecular mechanisms leading to the CMT are as varied as their genetic and related genes are translated by a wide variety of proteins with roles in central...
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