The structure and function of the central nervous system
depends on movements, carefully controlled, the neurons in formation. One of the
more complex neuronal migration and longer-range is given in the adult brain:
the neuroblasts born in the sub ventricular zone migrate from these walls to the
olfactory bulb. The question is how are oriented along a distance so large and
so complex territories.

A choral work responds to it, showing that the polarization of epithelial cells
provides important information for the migration of new neurons. Signing of the
Science article centers on the neurobiology and pathology of the University of
California, Columbia, Tokyo and Cleveland, and the company Genentech. The
Spanish contribution comes from the University of Valencia and Institutor de
Neurociencias de Alicante, the latter through the work of Oscar Marin, who has
been Youth Award for Science and Technology of the Universidad Complutense de
Madrid and EMBO Award.

And the answer is obtained by noting that the migration of neuroblasts occurs
following the course of cerebrospinal fluid (CSF). But the momentum required to
move the cilia of ependymal cells, as planar polarity is essential in the
formation of a concentration gradient of molecules that guide the migration of
neuroblasts in the adult brain. That is, the hair cells provide directional
information. These results, together with data from previous studies that
implicated the nodal cilia in left-right asymmetry, imply that the hair cells
with vector polarization provide important information for the physical
development plan.